Stars Who've Spoken About Ozempic — and What They've Said

Meghan Trainor, Oprah, Ashley Benson and more celebs who've talked about semaglutide drugs including Ozempic and Wegovy — and where they fall on its usage

Meghan Trainor attends the 2025 Billboard Women in Music; Eric Stonestreet at Norwegian Cruise Lines celebratory event; Oprah Winfrey attends the U.S. Dream Academy's 23rd annual Power of a Dream celebration
Meghan Trainor, Eric Stonestreet, Oprah Winfrey. Credit :

Axelle/Bauer-Griffin/FilmMagic; Alexander Tamargo/Getty; Paul Morigi/Getty

One of the hottest topics in Hollywood: The type 2 diabetes drug Ozempic and its fellow semaglutide drugs, including the obesity drugs Wegovy and Mounjaro. The use of either prescription — which Dr. Ania Jastreboff tells PEOPLE are "nutrient-stimulated, hormone-based medications" that target the brain and affect satiety. As a result, the GLP-1 drugs have become popular in Hollywood for weight loss both for those who only need to lose a few pounds as well as for those who have been open about their long-term weight struggles.

"The Hollywood trend is concerning," Dr. Caroline Apovian, co-director of the Center for Weight Management and Wellness at the Brigham and Women's Hospital in Boston, tells PEOPLE of the target audience for the drugs. "We're not talking about stars who need to lose 10 lbs. We're talking about people who are dying of obesity, are going to die of obesity."

Read on for what stars have said about the meds.

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Renee Graziano

Reality TV personality Renee Graziano visits SiriusXM Studios on March 5, 2018 in New York City.

Slaven Vlasic/Getty

"I’ve battled self-criticism in the past! Ripped myself down to the ground!! I truly was so sick and tired of my life and my inability to lose weight so I thought I’d eat until I felt better THAT NEVER HAPPENED, I felt like I was constantly falling short—of how I “should” look, feel, and keep up with what society tells us is acceptable.

That’s why, when I see photos that show the real, visible change, My clear eyes and genuine smile I have to share. I want everyone to know if I can do it you can do it! it’s all possible!!

The substantial amount of weight that I have lost really has made me feel and look younger than I have in a long time. My mind is clear and My body has transformed, and more importantly, so has my confidence.

Whatever goal you’re working toward, know this: you can do it. Be patient. Be kind to yourself. And don’t give up.”

—on taking Mounjaro for a 52-lb. weight loss, on Instagram

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Sophia Umansky

Sophia Umansky
Sophia Umansky.

Sophia Umansky/TikTok

"I am very lucky that I have so much hair because at the rate that I have been losing hair, I'm gonna be bald in about a week. I started Mounjaro about four months ago and I would say for the past three weeks to a month, I've noticed a dramatic hair loss situation..."

"I don't think it's a direct result of the medication, I think it's a direct result of rapid weight loss because of the medication and not eating enough vitamins, protein and all that kind of stuff. I feel like at the beginning of starting this medication, I was just making sure I was eating enough. I wasn't really thinking about enough protein or vitamins."

— in a TikTok video chronicling her hair loss

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Eric Stonestreet

 Eric Stonestreet 2025
Eric Stonestreet.

Alexander Tamargo/Getty

“It’s a game changer. It has just been incredible. It's changed my lifestyle, changed my approach to eating, changed my approach to exercise.”

“I felt like, well, if I don't do something along with it, I'm disappointing it. I'm letting it down. Here these people have invented this incredible thing that clearly does its part. Now I need to contribute my part. And it turns out that when you do that and make some really great choices, weight loss is also a byproduct of that.” 

—on taking Mounjaro to manage his health and weight, to PEOPLE

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Meghan Trainor

Meghan Trainor attends the 2025 Billboard Women in Music at YouTube Theater
Meghan Trainor.

Monica Schipper/WireImage

"No, I don’t look like I did 10 years ago. I’ve been on a journey to be the healthiest, strongest version of myself for my kids and for me. I’ve worked with a dietician, made huge lifestyle changes, started exercising with a trainer, and yes, I used science and support (shoutout to Mounjaro!) to help me after my 2nd pregnancy. And I’m so glad I did because I feel great.

Here’s to celebrating talent, growth, and the power of putting yourself first. Let’s keep shifting the convo to what REALLY matters."

on Instagram, after people kept commenting about her appearance at Billboard's 2025 Women in Music Awards.

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Josh Gad

Josh Gad attends the 77th Annual Tony Awards at David H. Koch Theater at Lincoln Center

Jamie McCarthy/WireImage

"[The GLP-1 drug] has suppressed, in a great way, that noise ... when I wake up, I feel hunger pains — and so much of that is psychological, right? — and what this does is it takes away that signal.

I've always been the funny fat guy. Can I be the funny skinny guy? Can I be the hot leading man? I don't know that people would accept me as those things.

It's a miracle drug ... My primary goal is, I want to be there for my kids. Everything else is bulls---."

on Armchair Expert about losing 40 lbs. on the medication

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Harvey Fierstein

Harvey Fierstein attends the Theatre Communications Group 2024 Gala : "Our Stories" Harvey Fierstein poses backstage at Watch What Happens Live;

Bruce Glikas/Getty; Manny Carabel/Getty 

“People don’t understand that being fat is not a choice. It’s something that your body is out of whack and [weight loss medication] puts your body in whack.

What’s different is what the drug actually does for you, which is: I don’t feel like I’m dieting. I feel like a normal person. I can go and have dinner with friends and not have to eat every piece of bread on the table, and then not go have ice cream when I’ve done with dinner.”

— to Page Six about his use of Zepbound

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Elon Musk

Elon Musk, co-founder and Chief Executive Officer of Tesla Elon dressed as santa claus

Robyn Beck-Pool/Getty Images; Elon Musk/X

“Ozempic Santa."

-on X (though he later added that he found Mounjaro to be more effective in his weight loss)

"Nothing would do more to improve the health, lifespan and quality of life for Americans than making [GLP-1 drugs] super low cost to the public."

on X

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Jim Gaffigan

Jim Gaffigan attends the 18th Annual Stand Up For Heroes event at Lincoln Center.
Jim Gaffigan.

Michael Loccisano/Getty

"I'm just grateful because it's such a better life."

"I had very low expectations because I did know someone that had tried it and they were like, 'Oh no, I was just nauseous for a week.' And then I thought my true joy of eating would overpower anything."

to PEOPLE, explaining how he lost 50 lbs. using Mounjaro

“I have gotten skinny. And it’s none of my own willpower. It’s a shot in the stomach. That works wonders. I don’t know why people are afraid to admit it. It seems strange.”

— on The View

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James Corden

James Corden attends PaleyFest LA 2023 - "The Late Late Show With James Corden" at Dolby Theatre on April 02, 2023
James Corden.

Jon Kopaloff/Getty

“I tried Ozempic, and it won’t be surprising to you when you look at me now, that it didn’t really work. I tried it for a bit and then what I realized was I was like, ‘Oh no, nothing about my eating has anything to do with being hungry.’ All this does is make you feel not hungry. But I am very rarely eating [just because of hunger].”

— on the Sept. 19 episode of his This Life of Mine podcast.

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Brooks Nader

Brooks Nader seen in Meatpacking District on November 08, 2024 in New York City.
Brooks Nader.

Aeon/GC Images

"Suspect randomly lost 20 pounds; says it's from working out, but she got on Ozempic,"

— one of Brooks Nader's sisters, in a TikTok video where they were doing the "suspect" challenge.

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Fat Joe

US rapper Fat Joe arrives to attend the MTV Video Music Awards at UBS Arena in Elmont, New York, on September 11, 2024.
Fat Joe in 2024.

ANGELA WEISS/AFP via Getty

 “Ozempic says you may only have two pieces of your favorite stuff.”  

— to Us Weekly while discussing how both the prescription medication and cutting carbs have helped maintain his 200-lb. weight loss

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Kathy Bates

Kathy Bates los angeles 05 02 24
Kathy Bates in 2024.

Steve Granitz/FilmMagic

“There’s been a lot of talk that I just was able to do this because of Ozempic, but I have to impress upon people out there that this was hard work for me, especially during the pandemic. It’s very hard to say you’ve had enough.”

to PEOPLE, while clarifying that in addition to the 80 lbs. she lost over the past seven years through changes in her lifestyle and diet, she lost another 20 lbs. on Ozempic.

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Bella Thorne

Bella Thorne attends the photocall at the 70th Taormina Film Festival on July 14, 2024
Bella Thorne in 2024.

Daniele Venturelli/Getty 

"So, I haven't been feeling good about my body for a while and especially with everybody on Ozempic — it's, like, setting all these crazy beauty standards that nobody can keep up with unless you're on Ozempic ... I'm finally feeling good, so Ozempic, you can [middle finger raised] off."

— in a video shared to her Instagram Story

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Ashley Benson

Ashley Benson attends the "McVeigh" premiere during the 2024 Tribeca Festival
Ashley Benson.

Jamie McCarthy/Getty

“I know a lot of people take Ozempic and that's totally fine. To each their own. But don't discredit people who also work very hard to get their body back like I've done with mine ... Getting back to work forced me to focus on my health and working out and I wanted to feel confident and good about myself."

— on her Instagram, after commenters speculated she'd taken the medication postpartum

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Ice Spice

Ice Spice poses in the press room at the 2023 MTV Video Music Awards on September 12, 2023 in Newark, New Jersey.
Ice Spice.

Taylor Hill/FilmMagic

"I wish y'all never learned the word Ozempic. That's one thing I wish. Oh my God, like, what even is Ozempic? What the f--- is that? Genuinely, what is that?

Like, you lazy ass bitches never heard of a gym? It's called the gym. It's called eating healthy. It's called being on tour. Like, what the hell? Maybe if I was sitting home all day, it would be easier to stay big."

during an X Spaces chat

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Macy Gray

NEW YORK, NEW YORK - SEPTEMBER 05: Macy Gray visits SiriusXM Studios on September 05, 2023 in New York City.
Macy Gray.

Noam Galai/Getty

“Quietly, I’m kind of a vain person. I’ve gained a lot of weight over the past couple years, and this is right about the time when everybody starts talking about this Ozempic.

So, I thought, okay, I’m not taking [the weight] off the right way, let me see if I can get one of these Ozempic. I was actually trying to take it off [the weight] before the show because I didn’t want to be super fat on TV, but here we are.”

During an episode of MTV's The Surreal Life

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Kandi Burruss

WATCH WHAT HAPPENS LIVE WITH ANDY COHEN -- Episode 20124 -- Pictured: Kandi Burruss Tucker
Kandi Burruss.

Charles Sykes/Bravo via Getty

“Last year, I tried it. I saw so many people who were trying it and losing weight. So I was like, ‘Okay, I’m going to try this.’ And I didn’t lose any weight.

My doctor was like, ‘I don’t know what the problem is, I’m not seeing this in other people,' ...It didn’t curb my appetite. I know some people are like, ‘Oh, I can’t eat.’ Not me! I was eating appetizers, a regular meal and dessert, okay? It didn’t stop anything for me.

When you see it worked for other people and it doesn’t work for you, it makes you depressed. Realistically, it makes you feel like, ‘What is wrong with me? Why is it not working for me?’”

— on PageSix’s Virtual Reali-Tea podcast

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Spencer Pratt

Spencer Pratt attends Prime Video and Freevee's Summer Solstice LA Event at the Santa Monica Proper Hotel on June 21, 2022 in Santa Monica, California.

Amanda Edwards/Getty

“I’m not trying to get Ozempic face. I’m not trying to be on Page Six coming out of a place, getting papped and looking all Skeletor [and] spooky.”

— explaining why he won't use semaglutide to help him lose weight, on the Page Six Virtual Reali-Tea podcast

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Nigella Lawson

Nigella Lawson attends the press night after party for "Nigel Slater's Toast" at The Other Palace on April 9, 2019

David M. Benett/Dave Benett/Getty

“I read something once where someone said, ‘I was on Ozempic and it was the first time I didn’t think about food all the time,’ and I thought, I can’t imagine anything worse than that. I take great pleasure in thinking about food all of the time.”

— to the New York Times

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Caroline Stanbury

Diving into Dubai Panel Caroline Stanbury

Greg Doherty/Bravo via Getty Images

“After 40, we all know, it’s very, very hard to lose weight. But I met so many 40-year-old women going, ‘How have you done it?’ And I don’t want to lie to you … I used Ozempic, which I think is one of the best tools if you’re able to use it. What did Kate Moss say? ‘Nothing tastes as good as skinny feels.’ There’s something to be said for that.”

— on the Uncut & Uncensored with Caroline Stanbury podcast

“Ozempic, I have to say … is an incredible tool. Why do you need to be miserable if you can get yourself back to where you were? I didn’t want to be different. I didn’t do my face to look like a supermodel. I wanted to be me, but younger.”

— to Us Weekly 

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Dr. Phil McGraw

CBS announced today that the new one-hour primetime series, HOUSE CALLS WITH DR. PHIL

Cliff Lipson/CBS via Getty

“If someone is using a tool to help them get back to health, help them lose weight, which takes the pressure off their heart, this isn’t something they should be criticized about. I say more power to ‘em and don’t feel guilty about it and don’t be shamed from people saying something about it. Tell them to mind their own damn business.”

— to Extra

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Captain Lee Roshbach

Captain Lee Rosbach

Karolina Wojtasik/Bravo/NBCU Photo Bank via Getty

“No. What you see, that’s what you get. I feel fortunate to be part of the lucky gene pool and what isn’t affected by the lucky gene pool I can usually affect by diet and working out.”

— on whether he would use semaglutide to stay in shape, via the Page Six Virtual Reali-Tea podcast

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Kelly Clarkson

THE KELLY CLARKSON SHOW -- Episode 7I127 -- Pictured: Kelly Clarkson
Kelly Clarkson.

Weiss Eubanks/NBCUniversal via Getty

"Mine is a different [drug] than people assume, but I ended up having to do that too because my bloodwork got so bad."

"My doctor chased me for two years, and I was like, 'No, I'm afraid of it. I already have thyroid problems.' Everybody thinks it's Ozempic, but it's not. It's something else."

"My heaviest, I was like 203 [lbs.] And I'm like 5-ft.3-in. and a half."

to Whoopi Goldberg on an episode of The Kelly Clarkson Show. Clarkson did not reveal the drug that she was taking but explained that the medication is "something that aids in helping break down the sugar," as her body "doesn't do it right."

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Khloé Kardashian

Khloe Kardashian
Khloé Kardashian.

 Frank Micelotta/Shutterstock

"Let's not discredit my years of working out. I get up 5 days a week at 6am to train. Please stop with your assumptions. I guess new year still means mean people."

— responding to an Instagram user who suggested she was on Ozempic

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Margaret Josephs

Margaret Josephs attends the OK! Magazine Summer Kickoff Party
Margaret Josephs. Theo Wargo/Getty

“After menopause, it’s so hard to lose weight. And then you’re shamed for it if you’re heavy."

“It shuts off that food noise, my blood work is great. [Before Ozempic] I couldn’t do anything. It doesn’t matter if I was eating right or exercising so I don’t know why there’s any shame in it if it’s helpful to people.”

to Sherri Shepherd on her podcast Sherri, after admitting she had struggled with her weight after menopause

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Jon Gosselin

Jon Gosselin attends the grand opening of Beverly Hills Rejuvenation Clinic West Hollywood
Jon Gosselin.

Paul Archuleta/Getty

“You know what’s annoying? The regret of not starting it 10 years ago. I feel amazing! Like, why didn’t I do this sooner? Maybe it wasn’t the right time.”

“It’s really nice because it helped me stop drinking and it helped me get my appetite under control with less eating. I was able to really refocus my diet that way, I just focused on consuming what I need to consume in a healthy manner.”

— to Page Six at the BHRC West Hollywood grand opening in April 2024

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Jamie-Lynn Sigler

Jamie-Lynn Sigler
Jamie-Lynn Sigler.

Jason Mendez/Getty

"I'm annoyed at myself that I'm admitting this and I'd like to get to the bottom of why I'm a little triggered about all the Ozempic stuff. It's upsetting me. I wish I didn't care. It felt like we were on this road to solidifying body positivity, and every shape and size and color, and everyone's looking the same now."

"For women out there listening, the thinner your face is, the older you look, okay? Not that looking old is bad!...Aging gracefully is beautiful."

to Christina Applegate on their podcast, MeSsy.

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Rebel Wilson

Rebel Wilson attends the amfAR Cannes Gala 2023
Rebel Wilson.

Mike Marsland/WireImage

“Someone like me could have a bottomless appetite for sweets, so I think those drugs can be good."

“Basically no one apart from my mom wanted me to lose weight. People thought I’d lose my pigeonhole in my career, playing the fat funny character, and they wanted me to continue in that.” 

“I feel strongly that young women shouldn’t try to obsess over looking like Victoria’s Secret models — they should just look like themselves. I know that my relationship with food is complicated."

to The Sunday Times in March 2024. Wilson also admitted that she is no longer on a weight loss drug, and that she is happy with her "still curvy and solid" current weight

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Christina P.

Christina P. visits Build Series at Build Studio on November 29, 2017 in New York City.
Christina P.

J. Kempin/Getty

“The doctor goes, ‘You know what, since you ate right through it last time, I'm going to start you on a higher dose.' And I'm like, ‘Alright, fair enough. I'm a pig.’

“I'm like, ‘Dude, I can't even [eat]. I feel nauseous. I can't even eat this bread. My mouth is dry. I feel like I'm gonna throw up.' And then I wake up in the middle of the night, like, super nauseous.

“I'm like, ‘This is working this time. I'm down, like, 3 lbs.'

"I take a bite. And I'm like, ‘Oh, I'm full. This feels great.’ You know?”

— while cohosting the Your Mom's House podcast with her husband Tom Segura. After a nurse friend came to visit, Christina P found out she had taken "enough [Ozempic] for, like, a 500-lb. man," per her friend.

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Tori Spelling

Tori Spelling Says She's Just Bought 1st Gift, Has 5 'Christmas Lists to Tackle' : 'Crushing This Single Mom Christmas'
Tori Spelling.

Taylor Hill/WireImage

“I did Mounjaro and everyone admits it now. It’s a different time so I don’t feel shamed saying that.

“I did whatever anyone told me to do that was safe and it just wasn’t working. The weight wouldn’t come off.”

— while discussing her usage of the tirzepatide and hormones on her podcast, misSPELLING, after admitting she had struggled with her weight after the birth of her fifth child, son Beau, in 2017. Spelling also said she is no longer on the drug.

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Mama June Shannon

V personality Mama June visits Build Series to discuss 'Mama June: From Not to Hot' at Build Studio on June 11, 2018 in New York City.
Mama June Shannon.

Desiree Navarro/Getty

“As you know, back in May 2015, I had gastric sleeve surgery. I used to weigh 550 lbs. and on my own, I went from 550 lbs. to 311 lbs. on the day I had my surgery. And in six weeks, I went from 311 all the way down to 195. Since then, I kinda kept off the weight. I stayed at like 130, 140, 150 lbs.”

“But I have noticed over the last year and a half that I’ve really put on weight."

“I decided to go with semaglutide a couple of months ago through my main doctor,” she said, urging people to be safe and talk to their primary care physician before taking the medication.

in an Instagram video posted on April 16, 2024. In the video, Mama June's husband even gives her her first injection

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Billie Jean King

Billie Jean King attends the WTA 50th Anniversary Gala
Billie Jean King.

Sarah Stier/Getty

“I'm a binge eater. Every morning I wake up, I tell myself I have an eating disorder. I still go to therapy. I still think about it. It's interesting with the new injections, you know, with the Ozempics of the world. It's very interesting because my doctor wants me to try it.”

“My therapist asked me, ‘Has it quieted your mind?’ With an eating disorder, I have two voices in my head sometimes that argue. Let's say I want a quart of ice cream. One side will say, ‘Yeah, baby, I'm going to have that ice cream no matter what.’ And the other side says, ‘No, don't do that. It's not healthy. You don't need it.’ So I have this discussion that goes on in my head, and sometimes it's very elevated.” 

“It was such a great question because if [weight loss medication] does quiet the voices – if that's a part of it – now I’m [interested in] it because that would be really great. Because that gets exhausting and tiring. And I don't wanna fight over these things.” 

— while discussing her use of weight loss injections and her eating disorder on Julia Louis-Dreyfus' Wiser Than Me podcast

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Oprah Winfrey

Oprah Winfrey attends the Los Angeles Red Carpet Premiere Event for Hulu's "The 1619 Project" at Academy Museum of Motion Pictures on January 26, 2023 in Los Angeles, California.
Oprah Winfrey. Alberto Rodriguez/GA/The Hollywood Reporter via Getty

"After knee surgery, I started hiking and setting new distance goals each week. I could eventually hike three to five miles every day and a 10-mile straight-up hike on weekends. I felt stronger, more fit and more alive than I’d felt in years.

"I eat my last meal at 4 o’clock, drink a gallon of water a day, and use the WeightWatchers principles of counting points. I had an awareness of [weight-loss] medications, but felt I had to prove I had the willpower to do it. I now no longer feel that way.

"I now use [an unnamed weight loss drug] as I feel I need it, as a tool to manage not yo-yoing. The fact that there's a medically approved prescription for managing weight and staying healthier, in my lifetime, feels like relief, like redemption, like a gift, and not something to hide behind and once again be ridiculed for. I’m absolutely done with the shaming from other people and particularly myself."

to PEOPLE in December 2023

"In my entire life, I never dreamed that we would be talking about medicines that are providing hope for people like me who have struggled for years with being overweight or with obesity."

— during her open-dialogue conversation An Oprah Special: Shame, Blame and the Weight Loss Revolution on ABC in March 2024

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Tracy Morgan

Image
Robin Marchant/Getty

"I went and got a prescription, and I got Ozempic. And I ain't letting it go ... It cuts my appetite in half. Now I only eat half a bag of Doritos."

— on Today with Hoda & Jenna in August 2023

“I’ve learned to out-eat Ozempic. I out-ate Ozempic. I’ve gained 40 pounds."

— on The Tonight Show Starring Jimmy Fallon in March 2024

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Terry Dubrow

BOTCHED -- Season: 8 -- Pictured: Dr. Terry Dubrow
Terry Dubrow.

Trae Patton/E! Entertainment via Getty

“I’ve tried it. I thought it was amazing. I didn’t have that much weight to lose. But I wanted to try it because so many of my patients were on it and I wanted to see what it was like when you’re not diabetic and you only have 10-15 pounds to lose.”

— speaking to Page Six after trying Ozempic in January 2024

"How am I doing off Ozempic? I'm overweight and chubby. There's more to love, but I'll tell you something: I'm off it, but I plan on going back on it when it's appropriate. Like we have a vacation and after that I'll come back. It's like the new Botox, Ozempic. I love it. It's so good."

— speaking to E! News in March 2024 about how he feels after stopping the medication

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Al Roker

Al Roker Addresses Health During Macy's Thanksgiving Parade
Al Roker.

Nathan Congleton/NBC via Getty

"Everybody’s struggling with it and we’re still trying to figure it out. But no shame, no game. Just stay within your lane and don’t give anybody a hard time."

— addressing judgement surrounding weight loss drugs in regards to Winfrey's televised discussion in March 2024

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Whoopi Goldberg

Whoopi Goldberg attends FGI Night of Stars 39th Annual Gala at The Plaza on October 17, 2023 in New York City
Whoopi Goldberg.

Dia Dipasupil/Getty

"I will tell you, I weighed almost 300 lbs. when I made [2022 film] Till. I had taken all those steroids, I was on all this stuff, and one of the things that’s helped me dropped the weight was the Mounjaro. That’s what I used."

on an episode of The View following Winfrey's ABC special

"First of all, it's all the weight I've lost. I've lost almost two people. I am doing that wonderful shot that works for folks who need some help, and it's been really good for me."

on an episode of The Kelly Clarkson Show, after Clarkson complimented Goldberg's appearance.

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Sunny Hostin

Sunny Hostin
Sunny Hostin.

Bonnie Biess/Getty

"During COVID, I gained 40. lbs. All I did was eat ... I love to cook, and I found out, I love to eat. And I was horrified about the fact that I would have to come out on air. So I also took Mounjaro.

"I found that my cholesterol went up to 200 when I gained the extra weight. And I use Mounjaro and my cholesterol is 140 now. I feel better, I think I look better, and that’s what this is about for people."

on an episode of The View following Winfrey's ABC special

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Stephen Fry

Stephen Fry is seen at the "Treasure" press conference during the 74th Berlinale International Film Festival Berlin at Grand Hyatt Hotel on February 17, 2024
Stephen Fry.

Sebastian Reuter/Getty

“I tried Ozempic years ago; I'm an early adopter of these things. I happened to be in America, and I'd read about it, and I asked my doctor in America, my physician as they like to call them, and he said, ‘I think I can get you some.’ He tried me on it, and the first week or so, I was thinking, ‘This is astonishing. Not only do I not want to eat, I don't want any alcohol of any kind. This is going to be brilliant.’ 

“Then I started feeling sick, and I started getting sicker and sicker and sicker. I was literally throwing up four, five times a day and I thought, ‘I can't do this.’ So that's it.”

speaking to host Ruthie Rogers on her River Café Table 4 podcast in March 2024

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Kate Winslet

Kate Winslet attends the L'Oréal Paris Lights on Women Award dinner at Hotel Martinez on May 27, 2022 in Cannes, France.
John Phillips/Getty

“Oh, my God. This sounds terrible. Let’s eat some more things!” 

to the New York Times, after they explained the drug to her, in March 2024

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Rob Lowe

Rob Lowe About last night netflix unstable

Emma McIntyre/Getty Images

“I see people who are taking all the new weight loss drugs and that's great, and it's really changed their lives. But my concern always is, okay, now what? What’s the plan for the longevity of everything? I never ever talk about diets, I talk about lifestyle."

to PEOPLE in February 2024

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Kelly Osbourne

Kelly Osbourne Drakes 08 29 23

Rachpoot/Bauer-Griffin/GC Images

"I think it's amazing. There are a million ways to lose weight, why not do it through something that's isn't as boring as working out? The people who hate on it the most are the people who are secretly doing it or pissed off that they can't afford it. Unfortunately, right now it's something that is very expensive but it eventually won't be because it actually works."

to E! Online in February 2024

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Sharon Osbourne

Sharon Osbourne attends the opening night of Black Sabbath - The Ballet at Birmingham Hippodrome on September 23, 2023 in Birmingham, England.
Sharon Osbourne.

Katja Ogrin/Getty 

“You can’t stay on it forever. I lost 42 pounds now and it’s just enough.” 

— on an episode of Piers Morgan Uncensored  where she opened up about her previous use of the drug, and added "I didn’t want to go this thin. It just happened."

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Heather Gay

Heather Gay attends 2023 Variety's Women Of Reality TV at Spago on November 29, 2023 in Beverly Hills, California
Heather Gay.

Monica Schipper/Getty

“I've been on it for a long time, but hadn't really seen much results. And I haven't had massive results, but enough for people to notice, which is great."

— to PEOPLE at Variety’s Women of Reality TV event in November 2023.

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Garcelle Beauvais

Garcelle Beauvais
Garcelle Beauvais. Rodin Eckenroth/WireImage

“Don’t even start with that Ozempic thing I’m not playing with that!!!”

— Iin response to an X commenter who shared a questioned if the reality had been using the drug.

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Claudia Oshry

Claudia Oshry Lemme Event ULTA New York 05 17 23
Claudia Oshry.

"You thought they were going to make a weight loss drug and I wasn't going to take it? You're dumb. Of course, I'm f—ing taking it."

— on her episode of her The Toast podcast while explaining that she initially felt embarrassed to admit she had been taking the weekly injections.

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Amy Schumer

TODAY -- Pictured: Amy Schumer on Wednesday, June 7, 2023
Amy Schumer.

Nathan Congleton/NBC via Getty Images

“Like a year ago, I tried it. I was one of those people that felt so sick and couldn’t play with my son. I was so skinny and he’s throwing a ball at me and [I couldn’t].”

— during an appearance on Watch What Happens Live with Andy Cohen

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Stassi Schroeder

recent photos of Stassi Schroeder
Stassi Schroeder.

Instagram/stassischroeder

“Oh, my God, I really want to try it when I give birth. The amount of times I’ve researched this being like, ‘I mean, I think it’s safe and healthy. Like, I think it’s good for you. It’s like taking vitamins.' ”

— discussing Ozempic on an episode of the Call Her Daddy podcast. Host Alex Cooper followed up the statement by jokingly giving a disclaimer that "nothing that was said on this podcast medically" should be understood as advice

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Lauren Manzo

Lauren Manzo of Bravo's reality TV series "Manzo'd with Children" visits SiriusXM Studio on September 9, 2016 in New York City.
Lauren Manzo.

Matthew Eisman/Getty

"I do think that people shouldn't abuse [Ozempic] ... I think it's being abused because I see people, Housewives, that are posting and you literally see their ribs, and it's sad because you were already skinny. And that puts a bad thing for somebody like me who has suffered from high blood pressure and anxiety from being super heavy and depression.

"People that are already 130 lbs. and just want to lose 10 more and they want to stay on it. That, I don't respect. I understand people with diabetes need that, and I respect that. I do think this will be really helpful for people like me, who've struggled their whole lives and had not only physical but mental issues as well from their weight."

— when talking about her experience on Mounjaro — an FDA-approved prescription medication for people with type 2 diabetes similar to Ozempic

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Emily Simpson

Emily Simpson BRAVOCON October 16, 2022
Emily Simpson.

Todd Williamson/Bravo/Getty

"So I did. I did that in December for one month," Simpson explained and added that her bad habits "went away... It made me more conscientious of what I was eating and so that was a really great kick start for me." 

— during an appearance on SiriusXM's Jeff Lewis Live where she spoke candidly about her decision to try Ozempic at her doctor's suggestion

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Golnesa 'GG' Gharachedaghi

Shahs of Sunset' Star Golnesa 'GG' Gharachedaghi Explains Why She Didn't Hide Her Ozempic Journey
Golnesa 'GG' Gharachedaghi.

Golnesa "GG" Gharachedaghi/Instagram

“When I started Semaglutide shots, I was 138 lbs. Now, I’m about 110 lbs. As you can see, I've lost a little more weight than I was anticipating to lose. I decided I’m only gonna weigh myself on the days of my injections just to document it. And on April 30, I got on the scale and I saw 111 lbs. That’s when I knew, it’s time to cut back. That’s when I started cutting down on units and going backwards and backwards until finally now, I’m just on maintenance.

“Will I come off of it? Maybe. Will I gain it all back? Maybe. But for now, I’m enjoying the way I look. I’m enjoying what it’s doing for me. I encourage it to anybody who’s having a hard time losing weight and wants the ‘easy route.’ Summer’s around the corner. I’m not trying to stress that being skinny is what you should do, but truth is, some of y’all want to do it. So I’m talking to you guys… not the haters. To the haters, kiss my ribs b—.”

— in a lengthy Instagram video answering questions about her weight loss journey

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Anthony Anderson

NEW YORK, NY - AUGUST 29 : Anthony Anderson attends the victory of Serena Williams of USA on Day 1 of the US Open 2022, 4th Grand Slam of the season, at the USTA Billie Jean King National Tennis Center on August 29, 2022 in Queens, New York City. (Photo by Jean Catuffe/GC Images)
Anthony Anderson. Jean Catuffe/GC Images

"I will say this, it's creating a shortage for those of us who need the medicine that we need and not for weight loss issues, but for our health."

— when talking to PEOPLE about how the drug's newfound popularity impacts those like him who are living with type 2 diabetes

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Jessica Simpson

Jessica Simpson
Jessica Simpson. Kevin Mazur/Getty Images

“Oh Lord… it is not."

— while addressing assumptions that her weight loss is due to the use of a semaglutide in an interview with Bustle

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Jenny McCarthy

Jenny McCarthy attends day 3 of SiriusXM at Super Bowl LIV
Jenny McCarthy.

Cindy Ord/Getty

​​“You know what, I think whatever suits someone’s needs. If you fall into the category where you think it’s right for you, I am not gonna shame you. I’ll support anything people want to do. For me in particular, I knew that it was not permanent, I knew that a lot of people that go off of it, they regain their weight.” 

— while discussing why she's "not an Ozempic person" in an interview with US Weekly

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Mark Wahlberg

Mark Wahlberg - Fotos International - Getty Images Entertainment - GettyImages-72207969
Mark Wahlberg. Mark Wahlberg - Fotos International - Getty Images Entertainment - GettyImages-72207969

"Everybody has their own path. I don't knock anybody for making their own choices. But I prefer, and I've seen lots of people accomplish amazing things, ordinary people doing extraordinary things on a fitness base, and they're now encouraging other people that look like them. That's what I'm into."

— while discussing how he feels about those deciding to use semaglutide for weight loss in an interview with Page Six

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Raven-Symoné

Raven-Symone
Raven-Symoné in Beverly Hills on March 30, 2023.

Monica Schipper/Getty

"I think it's very important we understand certain medications are made for certain people and to not take that away just for glamazon purposes.

“Do what you gotta do. Just make sure you save some medication for the people that actually need it," she added

— in an interview with E! News

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Keke Palmer

keke palmer
Frazer Harrison/Getty

"Sounds like it's a slay honey, 'cause girls have been out here killin' it with it, but for me, I would say 'Nay' because I always feel like when something sounds too good to be true — it usually is.

"It might do something and then next thing you know, I've got something growing, you know, under my armpits, like I don't know where... where you pushing this fat at, where you taking, where you pulling from — I don't want any side effects, so — but the girls are killin' it."

— during a round of "Slay or Nay" for PEOPLE's Beautiful Issue

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Padma Lakshmi

adma Lakshmi attends Global Citizen Live, New York on September 25, 2021 in New York City.
Noam Galai/Getty

"You gotta be careful what you do with your body. On Top Chef I eat a lot, and I understand the tendency [to want to follow a weight loss trend]. But also the pressure for women in media is much different than men in media. So we have to maybe look deeper to the reasons why, as a society, not just put it on the shoulders of the women who just want the same opportunity that men get.

"We just want an equal shake. We have to look good, we have to sound good, we have to be strong but not too strong, we have to be vulnerable but not too weak. And it can feel like a really dichotomous, tall order.

"So, I think we have to be kinder to each other and to ourselves."

— to reporters at the 2023 Time100 gala

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Ariana Huffington

775086218BT00113_2018_Break
Jesse Grant/Getty

"Well, if people are diabetic it can really help them. But I think people forget that you also need to eat better. You know, if you are on Ozempic and eat junk, processed foods, too much sugar, you are not going to really change your eating habits. And we know that what leads to disease are ultra processed foods and sugar."

"So, learning to also change your food habits is key."

— to PEOPLE at the 2023 Time100 gala

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Sophie Turner

Sophie Turner attends 2023 Vanity Fair Oscar After Party
Getty

"WTF"

- on her Instagram Story, in response to photos of semaglutide advertisements posted inside a New York City subway station, per The Independent

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Dolores Catania

Dolores Catania 'A Good Person' film screening, New York, USA - 20 Mar 2023
Stephen Lovekin/Shutterstock

"I wasn't going to come to [the] reunion looking bigger than anyone else."

to Andy Cohen on WWHL, confirming she uses a weight loss drug

"I'm down 20 pounds. I'm being realistic. Right now, I'm 137. I was 157 when I started. I jumped to 163 - I was going there. Like, I was gaining weight every month. So then when I finally kicked in... the problem is, like, if you don't start it, it takes time to work. It doesn't happen overnight. It doesn't come off easy. I took Ozempic, stopped and then began Mounjaro,” she explained. “I was medically prescribed for both because I am insulin resistant/pre-diabetic and have a thyroid issue. You know, everyone's losing so much weight [on it]. It's questionable - what are the repercussions of this when everyone's done? Is there side effects? All the doctors that I spoke to said 'no.'

"I stopped taking it because it was expensive and everything. But being healthy and living a healthy lifestyle is cheap - it's free!" she insisted. I work out regularly. There is no easy fix for weight loss and I have to watch what I eat."

to the U.S. Sun in 2023.

“I don’t know why because there’s no shame in it. If a doctor gives it to you, if you’re doing things right, you’re becoming healthier by losing weight. It’s a bunch of great things that come along with this.”

"This is my high school weight. I’m not parting with it and I’m gonna be honest because it’s right."

to Sherri Shepherd on an episode of Shepherd's self-titled talk show Sherri about why some celebrities keep their medication usage quiet.

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Julia Fox

Julia Fox
Jerritt Clark/Getty

"All these people are coming for me saying that I take the weight-loss things … people are saying that I'm taking Ozempic. I'm not, and I never have. I would never do that. There are diabetics that need it."

to Entertainment Tonight in March 2023

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Meghan McCain

Mandatory Credit: Photo by Matt Baron/Shutterstock (12918939kk) Meghan McCain White House Correspondent's Dinner, Washington, D.C, USA - 30 Apr 2022
Matt Baron/Shutterstock

"I was even offered a black market freebie by someone with 'extra shots at home.' ... Let me make one thing very clear. I'm not taking it. I refuse. There's a clear moral issue here. It's hard to take a drug because swimsuit season is around the corner, while others need it to stay alive. And how can this be healthy? There ain't nothing worth having that's easy to get."

in an op-ed for the Daily Mail about being offered weight loss drugs while postpartum

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Jillian Michaels

Jillian Michaels Slams Keto, Promotes Intermittent Fasting and Weighs in on Other Fad Diets
Getty Images

"[I've] taken at least eight family friends' parents off of this drug. The truth of the matter is, Ozempic has some pretty significant side effects. Do your homework on it. The results are not lasting, in very large part,"

— to PEOPLE

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Patti Stanger

"Millionaire Matchmaker" Patti Stanger
Vivien Killilea/Getty

"This is the Hollywood drug ... It's nationwide. I have friends in Miami, I have friends in New York who are doing it."

to the Wall Street Journal in October 2022, before opening up about her own experience with Ozempic and Mounjaro on the Behind the Velvet Rope podcast in February 2023

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Katie Maloney

Vanderpump Rules -- Season 10 Premiere Party -- Pictured: Katie Maloney
Todd Williamson/Bravo via Getty

"I say everyone do what you want to do. Understand the risks, and if it's right for you, it's right for you. I think the expectations [for women to be thin] are always going be there whether or not there's like this miracle drug or not. The pressures are always going to be there. So thanks, Hollywood, thanks media, thanks society for keeping it going. But I just think, you know, if it makes you happy, follow your bliss."

to PEOPLE at the premiere of Vanderpump Rules season 10

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Lala Kent

Lala Kent attends Travel & Give Fundraiser with Lisa Vanderpump at Tom Tom on October 11, 2021 in West Hollywood, California
Lala Kent. Alberto E. Rodriguez/Getty

"Stop taking it for weight loss. Enough already. I think that Hollywood is all sorts of f—ed up. We've got to do better. I think there's a lot of things that need to change and it starts with us and there are times where I roll my eyes and say, 'F—ing do better, all of us. We all need to participate in becoming better examples for our children in the outside world."

to PEOPLE at the premiere of Vanderpump Rules season 10

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Kyle Richards

Kyle Richards The American Heart Association's Go Red For Women Red Dress Collection
Kyle Richards. Erik Pendzich/Shutterstock

"I cannot stand people saying [I'm taking Ozempic] because people that know me know that I'm up every day at like 5:30 a.m. 6 a.m. at the latest… I'm in the gym for two hours. I really put a lot of effort into my diet and exercise and taking care of myself, so when people like to think I took the easy way out, it's frustrating."

to Extra at the American Heart Association's Go Red for Women Red Dress Collection concert in New York City, after she recently clapped back at commenters who suspected she's using the drug after posing a bikini selfie

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Chelsea Handler

Critics Choice Award Arrivals
Frazer Harrison/Getty

"My anti-aging doctor just hands it out to anybody. I didn't even know I was on it. She said, 'If you ever want to drop five lbs., this is good.'

"I came back from a vacation and I injected myself with it. I went to lunch with a girlfriend a few days later, and she was like, 'I'm not really eating anything. I'm so nauseous, I'm on Ozempic.' And I was like, 'I'm kind of nauseous too.' But I had just come back from Spain and was jet-lagged.

"I'm not on it anymore. That's too irresponsible. I'm an irresponsible drug user, but I'm not gonna take a diabetic drug. I tried it, and I'm not gonna do that. That's not for me. That's not right for me.

"I've injected about four or five of my friends with Ozempic because I realized I didn't wanna use it cause it's silly. It's for heavy people. Everyone is on Ozempic. It's gonna backfire, something bad is gonna happen."

on Alex Cooper's Call Her Daddy podcast

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Remi Bader

Remi Bader attends Variety, The New York Party at American Bar on October 19, 2022 in New York City.
Jamie McCarthy/Variety via Getty

"[My doctors] said I need this. And I had a lot of mixed feelings. A few months later I went off it and got into the bad binging.

"I saw a doctor and they were like, it's 100 percent because I went on Ozempic. It was making me think I wasn't hungry for so long, I lost some weight. I didn't wanna be obsessed with being on it long term. I was like, I bet the second I got off I'm gonna get starving again. I did, and my binging got so much worse. So then I kind of blamed Ozempic. [I] gained double the weight back."

on Amanda Hirsch's Not Skinny But Not Fat podcast

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Jackie Goldschneider

NEW YORK, NEW YORK - OCTOBER 14: Jackie Goldschneider attends 'Legends Ball 2022 BravoCon' at Manhattan Center on October 14, 2022 in New York City. (Photo by Santiago Felipe/Getty Images)
Jackie Goldschneider at the 'Legends Ball 2022 BravoCon'. Santiago Felipe/Getty

"An eating disorder in a needle. [It's] sad and sickening. [I] can't imagine what will happen if people need to suddenly stop."

on Instagram

"I'm horrified by it. I'm not so much horrified by people wanting to lose weight — that has always been a universal thing — but I'm very very scared of what will happen if and when people have to go off this drug.

"It's just going to be a massive number of people who gain a huge amount of weight and suddenly don't know what to do with themselves. I'm just afraid of that day. There's going to be a lot of people with eating disorders. You start dropping massive amounts of weight. That's so addicting. That's how I spiraled into anorexia. You get addicted to this new body and to the attention that comes with it.

"A lot of people in the Housewives world are on Ozempic. A lot of my friends are in the Housewives world, so it was tough for me to come back and suddenly no one's eating when we go out to dinner."

on the Page Six Virtual Reali-Tea podcast

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Andy Cohen

ew Season Press Junket in New York City on Monday, May 16, 2022 -- Pictured: Andy Cohen, Watch What Happens Live with Andy Cohen on Bravo
Cindy Ord/NBCUniversal/NBCU Photo Bank via Getty

"Everyone is suddenly showing up 25 pounds lighter. What happens when they stop taking #Ozempic ?????"

on Twitter

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Elon Musk

Elon Musk attends TIME Person of the Year on December 13, 2021 in New York City.
Elon Musk. Theo Wargo/Getty

"Fasting ... And Wegovy."

replying to a Twitter user asking for his "secret" to looking "healthy"

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Jameela Jamil

The 24th Annual Critics' Choice Awards - Red Carpet
Jameela Jamil arrives at the 24th Annual Critics Choice Awards. Kevin Mazur/Getty Images

"I have said what I have said about the potential harm of people using the diabetes medication for weight loss only. I fear for everyone in the next few years. Rich people are buying this stuff off prescription for upwards of 1000 dollars. Actual diabetics are seeing shortages. It's a now mainstream craze in Hollywood. HOPE this doesn't end the same way we were told opioids were safe. There is little to no discussion of the side effects in any advertising online. I'm deeply concerned but I can't change any of your minds because fat phobia has our generation in a chokehold.

"I'm screaming into a void. I'm seeing people really struggle because of this stuff. It has become the exact uncontrollable wave I thought it would become and I hope that I'm worried for no reason, and that my doctors who have been advising me on this stuff are wrong, and that in 2 years nobody is saying 'F--- she was right and she tried to warn us for 6 months.'

"Wishing you all well and hope you have doctors that care about more than your size."

on Instagram

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