The lowest dose of estrogen prescribed for menopause varies depending on the individual, their needs, and the form of estrogen being used.

Doctors generally recommend starting with the lowest effective dose to manage symptoms of menopause while minimizing potential risks.

The specific dose and form used should be determined in consultation with a doctor. A doctor can tailor the dose and form of estrogen to meet your individual symptoms and health profile.

What is low-dose estrogen typically used for?

Low dose estrogen replacement medications can help relieve:

Estrogen is the primary hormone that doctors prescribe for symptoms of menopause. Estradiol is a lab-made form of estrogen.

The table below shows the different forms of estradiol and their equivalent doses.

FormUltra low doseLow doseMedium doseHigh dose
Oral0.5 mg1.0 mg2.0 mg3 to 4 mg
Patchhalf 25 mg patch25 mg patch50 mg path75 to 100 mg patch
Gel-pump1/2 pump1 pump2 pumps3 to 4 pumps
Gel-sachet1/2 x 0.5 mg sachet to 0.25 mg0.5 mg1 to 1.5 mg2 to 3 mg
Spray1 spray2 sprays3 sprays

If you’ve been experiencing symptoms of menopause that are disrupting your life, make an appointment with a doctor. They can discuss the benefits and risks of hormone therapyTrusted Source and recommend a form and dose that’s right for you.

According to the British Menopause Society, some people respond well to one form of estradiol and don’t respond well to another. If you’ve been prescribed a certain dose or form and it’s not working, let your doctor know.