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⚠️ “Hidden” side effects of GLP-1 drugs: A recent study used self-reported Reddit data to examine the real-world effects of these medications beyond the disclaimers we see in ads and marketing. The research found various “hidden” side effects, such as menstrual irregularities, chills, hot flashes, and fatigue. (Read more about what the researchers discovered.)
🧠 Potential mental health benefits of GLP-1s: Researchers are increasingly interested in examining the effects of GLP-1 medication beyond weight loss and diabetes management. Recent studies have shown positive benefits for reducing impulsivity and violent behaviors and managing depression, anxiety, and binge eating disorder. (Read more about how these drugs may support mental well-being.)
👀 A new self-reported side effect: GLP-1 users have reported various unusual side effects, like “Ozempic teeth,” “Ozempic butt,” and “Ozempic personality.” Now, fingernails have entered the chat. According to a new study, nail detachment and discoloration may be four times more common among people taking these drugs. (Read more about this research and how to protect your hair and nails while using a GLP-1.)
🏥 Generic Mounjaro, Zepbound may be coming soon: Federal regulators have agreed to review applications for two cheaper generic versions of the tirzepatide medications. The Food and Drug Administration (FDA) hasn’t specified how long this process will take, but on its website, the agency states that it typically completes reviews of standard drug applications within 10 months. (Read more about what this means for affordability and access.)
🌟Actor Mayim Bialik shares her “nightmare” GLP-1 experience: Of course, there are many success stories and people who have minimal side effects. But Mayim Bialik is not one of them. After one low dose injection, she said she began to experience gastrointestinal symptoms that left her unwell for weeks. “To say I had an adverse reaction would be somewhat of an understatement,” she says. (Read more about why she turned to GLP-1s and how her autoimmune disease symptoms may have exacerbated her side effects.)
🫀 One way to lower your heart health risk: GLP-1 medications like semaglutide and tirzepatide have reshaped care for people with type 2 diabetes (T2D), but recent real-world evidence suggests these drugs may differ in the level of heart protection they offer. For example, an observational study found that people with T2D who increased their Ozempic dosage had a lower risk of major adverse cardiovascular events (MACE) compared to those who switched to Mounjaro. (Read more about how different GLP-1s can affect your heart.)
⚖️ Trial finds two strategies to maintain weight loss results: A popular concern after stopping GLP-1 medications is regaining weight. One study suggests that structured support, such as using wellness apps or eating meals developed by dietitians, may help minimize the weight regain that can occur shortly after discontinuing use. (Read more about this study and what the findings mean for maintaining weight loss after GLP-1s.)
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